Mother knows best

Genome Rearrangements: Mother Knows Best!

In Paramecium, developmentally programmed genome rearrangements can be altered by the presence of homologous sequences within the maternal somatic nucleus. Newly identified RNA-binding proteins appear to mediate the transfer of homologous sequence information from the maternal to the developing somatic nucleus, facilitating epigenetic regulation of this large-scale genome reorganization.

Mother knows best: maternal influence on early embryogenesis.

Mother Knows Best: Dominant Females Determine Offspring Dispersal in Red Foxes (Vulpes vulpes)

BACKGROUND Relatedness between group members is central to understanding the causes of animal dispersal. In many group-living mammals this can be complicated as extra-pair copulations result in offspring having varying levels of relatedness to the dominant animals, leading to a potential conflict between male and female dominants over offspring dispersal strategies. To avoid resource competitio...

Mother still knows best: cancer-related gene mutations, familial privacy, and a physician's duty to warn.

The vows of the Hippocratic Oath which include a vow to abstain from sharing a patient’s personal information remains an important tenet of medical care today. Physician-patient confidentiality even abstains sharing information with patients’ families. However, when medical information affects the health of the patient’s relatives, many medical professionals assert that they have a duty to shar...

Have you seen ? “ Father knows best ? ” Ashley

Following fertilization, activation of a complex developmental program requires the differential expression of key genes. In most metazoa, the prevailing view is that early differential gene expression occurs primarily through post-transcriptional regulation of maternally deposited products in the oocyte. Two novel studies published from the Rajewsky laboratory in this issue of The EMBO Journal...